GUDMAP Projects
GUDMAP 4
Funding period: 2021 through 2026 (RFA-DK-20-013)
The goal of this phase of GUDMAP is to establish a comprehensive understanding of kidney and lower urinary tract development and maturation to inform the study of tissue maturation and aging, organ dysgenesis and disease, and ultimately organ repair and regeneration.
- Creating high-resolution multi-omics molecular atlases for developing urogenital organs (Feng Chen, Washington University, St. Louis)
- Diversification of cell types during male and female external genital development (Marty Cohn, University of Florida)
- Building a multi-scale vascular atlas of the mouse lower urinary tract (Janet R. Keast, University of Melbourne)
- High resolution transcriptome and gene regulatory mapping of human ureter and bladder across the lifespan (Byron H. Lee, Cleveland Clinic Lerner COM-CWRU)
- Regulation of prostate organogenesis by tissue-resident macrophages (Maho Shibata, The George Washington University)
- The single and same cell 3D atlas of epigenome and transcriptome of the lower urinary tract (Xue Sean Li, Cedars-Sinai Medical Center)
GUDMAP 3
Funding period: 2016 through 2021 (RFA-DK-15-015)
Main focus is expanding our understanding of human development of the genito-urinary system.
- Mapping Molecular Regionalization of Cell Types along the Anterior-Posterior Axis of the Urethra (Marty Cohn, University of Florida)
- GUDMAP Tissue Hub and Collection Site (Rajiv Dhir, University of Pittsburgh)
- GUDMAP Coordinating Center (Carl Kesselman, University of Southern California / M. Todd Valerius, Brigham and Women's Hospital, Harvard Medical School)
- Li Group (Sean Li, Cedars-Sinai Medical Center)
- Four-Dimensional Modeling of Mouse and Human Nephrogenesis (Andrew McMahon, University of Southern California)
- Generating an Atlas of the Developing Human Urinary Outflow Tract (Cathy Mendelsohn, Columbia University)
- Atlas of Autonomic and Neuromodulatory Lineages in the Developing Lower Urinary Tract (Michelle Southard-Smith, Vanderbilt University Medical Center)
- A Cellular Atlas of the Normal Human Prostate (Doug Strand, University of Texas Southwestern Medical Center)
- Molecular and Fate Maps of Prostatic Stroma (Chad Vezina, University of Wisconsin-Madison)
- Understanding Functional Connectivity of Sensory and Motor Pathways to Specific Regions of the Lower Urinary Tract (Janet Keast, University of Melbourne)
GUDMAP 2
Funding period: 2011 through 2016 (RFA-DK-11-001)
Main focus is lower urinary tract (includes human GUDMAP extension).
Project descriptions for GUDMAP 2 :
GUDMAP 1
Funding period: 2005 through 2011 (PAR-04-042)
Main focus was the kidney, also minor focus on reproductive system, bladder, pelvic region and prostate.
Project descriptions for GUDMAP 1:
- Blanche Capel
- Kevin Gaido
- Duncan Davidson (Editorial Office and Database Core)
- Jim Lessard
- Melissa Little
- Andy McMahon
- Cathy Mendelsohn
- Steve Potter
- Michelle Southard-Smith
- Chad Vezina
- Pumin Zhang
nGUDMAP
Funding period: 2013 through 2015 (RFA-DK-12-024)
Focus on nociceptors (pain receptors) and associated cell types in pain processing of the urinary tract and pelvic region.
Project descriptions for nGUDMAP:
- Gerard Ahern
- Richard Baldock
- Edinburgh Core Database
- Sanjay Jain
- Michelle Southard-Smith
- Janet Keast
The original database design & implementation is credited to Derek Houghton (derek.houghton@igmm.ed.ac.uk)
